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LATEST UPDATES » Vol 22, No 11, November 2018 – The Asian Cancer - War on liver cancer       » 2018 Nobel Prize in Physiology or Medicine winners       » Women more prone to selected chemotherapy side effects       » Tibetan fungus could help fight liver cancer       » Standards for TCM decoction to be applied globally       » RMB200 million donation to build Tsinghua University Biomedical Sciences Building      
EYE ON CHINA
Heart-on-a-chip device to aid drug screening
Chinese scientists have developed a device to mimic the contractions of cardiac muscle cells, which can potentially replace human and non-human animal models for drug screening.

Chinese scientists have developed a "heart-on-a-chip" device to mimic the beat and contraction of cardiac muscle cells in vitro, which could replace non-human animal models for drug screening.

"Organ-on-a-chip" research mainly involves designing an inch-long silicone device that houses a network of organ cells, which can effectively model human organs and show results for drug tests.

A research team led by Zhao Yuanjin from the state key laboratory of bioelectronics at China's Southeast University has successfully added a structural color hydrogel into a heart-on-a-chip and predicted its clinical values. Their findings were published in the journal, Science Robotics in March.

The research was inspired by the biological properties of chameleons. Once the color hydrogel is injected into the chip, it showed color changes according to the contraction of cardiac muscle cells.

When related medication is adopted for some specific heart diseases, the conditions of the cardiac muscle cells can be monitored through the color-changing hydrogel, said Zhao.

"This device focuses on building new platforms for the testing and development of new drugs for safety and efficacy. It will not only replace human and non-human animal models for drug screening, but also meet the medical needs of individual patients in the future," Zhao said.

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NEWS CRUNCH  
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news 2018 Nobel Prize in Physiology or Medicine winners
news Vitafoods Asia expands by 40 per cent in 2018
PR NEWSWIRE  
Asia Pacific Biotech News
EDITORS' CHOICE  
COLUMNS  

APBN Editorial Calendar 2018
January:
Obesity / Outlook for 2018
February:
Searching for the fountain of youth
March:
Women in Science - Making a difference
April:
Digestive health in the 21st century - Trust your guts
May:
Dental health - The root to good health
June:
Cancer - Therapies and strategies for better patient outcomes
July:
Water management - Technologies for biotech and pharmaceutical industries
August:
Regenerative technology - Meat of the future
September:
Doctor Robot - The digital healthcare revolution
October:
Bones / Breast cancer
November:
Liver health / Top science research nations & institutions
December:
AIDS / Breakthrough of the year/Emerging trends
Editorial calendar is subjected to changes.
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