HOME ABOUT CONTACT AVAILABLE ISSUES SUBSCRIBE MEDIA & ADS
LATEST UPDATES » Vol 23, No 03, March 2019 – Driven by curiosity — Exclusive interview with Nobel laureate Ada Yonath: Her journey in science wasn't always crystal clear       » Your eyes don't deceive you, your brain does       » Organ donations to be computerised in China       » Over One tenth of Chinese people have mental health problems       » AI system can diagnose childhood diseases like doctors       » Bitter rapeseed potential protein source for human nutrition      
EYE ON CHINA
LncBook: a curated knowledgebase of human long non-coding RNA
Features a comprehensive collection of human lncRNAs and associated data

Long non-coding RNAs (LncRNA) have a variety of functions in many important biological processes and are closely associated with various diseases. Although the number has dramatically increased, the known human lncRNAs are poorly annotated, posing great challenges for understanding their functional significance and elucidating their complex functioning molecular mechanisms.

Recently, BIG Data Center, Beijing Institute of Genomics of Chinese Academy of Sciences (CAS) collaborating with Prof. Vladimir Bajic of King Abdullah University of Science and Technology (KAUST), released a curated knowledgebase of human lncRNAs-LncBook. This work was published online in Nucleic Acids Research on 17 October 2018.

LncBook features a comprehensive collection of human lncRNAs and systematic curation of lncRNAs by multi-omics data integration, functional annotation and disease association.

The current implementation of LncBook houses a large number of 270,044 lncRNAs and includes 1,867 featured lncRNAs with 3,762 lncRNA-function associations. It also integrates an abundance of multi-omics data from expression, methylation, genome variation and lncRNA-miRNA interaction.

In addition, LncBook includes 3,772 experimentally validated lncRNA-disease associations and identifies a total of 97,998 lncRNAs that are putatively disease-associated. Equally important, LncBook organises all relevant data in a structured manner, facilitating data browse/search with more enhanced efficiency, and provides several useful tools for online analysis.

LncBook is dedicated to the integration and curation of human lncRNAs as well as their associated data and thus bears great promise to serve as a valuable knowledgebase for worldwide research communities.

Source: Chinese Academy of Sciences

Click here for the complete issue.

NEWS CRUNCH  
news Which country has the worst sleepers
news Asia is the fastest growing region for nutraceuticals
news 2018 Nobel Prize in Physiology or Medicine winners
news Vitafoods Asia expands by 40 per cent in 2018
PR NEWSWIRE  
Asia Pacific Biotech News
EDITORS' CHOICE  
COLUMNS  

APBN Editorial Calendar 2019
January:
Taiwan Medical tourism
February:
Marijuana as medicine — Legal marijuana will open up scientific research
March:
Driven by curiosity
Editorial calendar is subjected to changes.
MAGAZINE TAGS
About Us
Events
Available issues
Editorial Board
Letters to Editor
Instructions to Authors
Advertise with Us
CONTACT
World Scientific Publishing Co. Pte. Ltd.
5 Toh Tuck Link, Singapore 596224
Tel: 65-6466-5775
Fax: 65-6467-7667
» For Editorial Enquiries:
   biotech_edit@wspc.com or Ms Lim Guan Yu
» For Subscriptions, Advertisements &
   Media Partnerships Enquiries:
   biotech_ad@wspc.com
Copyright© 2019 World Scientific Publishing Co Pte Ltd  •  Privacy Policy