HOME ABOUT CONTACT AVAILABLE ISSUES SUBSCRIBE MEDIA & ADS
LATEST UPDATES » Vol 23, No 01, January 2019 – Taiwan medical tourism - Combining medical travel and tourist destination       » New breast cancer drug now available in China       » Chinese scientists make important cancer finding       » Japan's plan to revolutionise healthcare sector with tech       » GSK to buy oncology drugmaker Tesaro for US$5.1 billion       » There is hope for anticancer vaccines      
EYE ON CHINA
Chinese scientists make important cancer finding
Protein called FBXO38 found to affect body's anti-tumour immunity

Chinese scientists have discovered a protein called FBXO38 that affects the body's anti-tumour immunity, providing possible new insight into cancer immunotherapy.

In vitro studies by a group of researchers from the Chinese Academy of Sciences' Shanghai Institute of Biochemistry and Cell Biology have shown that a low amount of FBXO38 leads to the accumulation of more PD-1 than the body requires. PD-1 is a molecule that helps keep the body's immune responses in check.

Scientists found out many years ago that tumour cells often multiply and develop by finding ways to over-activate PD-1, which in turn impairs the body's ability to destroy tumour cells.

The Chinese research paper, which took seven years to complete, was published on Nature.

The scientists also found that an FDA-approved drug called IL-2, which is used to treat skin and kidney cancers, can boost the levels of FBXO38 in the tumour microenvironment to improve the effectiveness of killing cancer cells.

However, this drug has not been widely used for its obvious side effects, including vascular leakage and inflammation, the researchers said.

"One possible approach in clinical application might be optimising the form of the drug and its dosage in the future and exploring its combined use with other therapies," said Xu Chenqi, the lead researcher.

Source: China Global Television Network

Click here for the complete issue.

NEWS CRUNCH  
news Asia is the fastest growing region for nutraceuticals
news 2018 Nobel Prize in Physiology or Medicine winners
news Vitafoods Asia expands by 40 per cent in 2018
PR NEWSWIRE  
Asia Pacific Biotech News
EDITORS' CHOICE  
COLUMNS  

APBN Editorial Calendar 2019
January:
Taiwan Medical tourism
Editorial calendar is subjected to changes.
MAGAZINE TAGS
About Us
Events
Available issues
Editorial Board
Letters to Editor
Instructions to Authors
Advertise with Us
CONTACT
World Scientific Publishing Co. Pte. Ltd.
5 Toh Tuck Link, Singapore 596224
Tel: 65-6466-5775
Fax: 65-6467-7667
» For Editorial Enquiries:
   biotech_edit@wspc.com or Ms Lim Guan Yu
» For Subscriptions, Advertisements &
   Media Partnerships Enquiries:
   biotech_ad@wspc.com
Copyright© 2019 World Scientific Publishing Co Pte Ltd  •  Privacy Policy