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LATEST UPDATES » Vol 23, No 11, November 2019 – Evaluating cost effectiveness of genomic profiling       » Ion treatment offers new hope for cancer patients       » Empowering sustainability through innovation       » Meeting clinical needs in Asia with HealthTech       » The key in diagnosis and treatment       » Singapore's first private co-working laboratory and office space       » Singapore-based MedTech company announced as winner of 2019 Asia Pacific Showcase Competition at The MedTech Forum      
INSIDE INDUSTRY
Proteona releases CAR T characterisation product
Innovative genomic and proteomic analysis platform for cell therapy and immuno-oncology

Proteona announced the launch of its latest ESCAPE proteogenomics assay designed specifically for Chimeric Antigen Receptor (CAR) T cell characterisation.

This is the first commercial product designed to characterise both RNA and protein expression levels across thousands of single CAR T cells.

Through the use of simultaneous gene and protein expression analysis, the ESCAPE CAR T assay is able to identify CAR positive cells, measure changes in cytokine expression, deeply phenotype cells through measuring the expression of 25 key cell surface proteins and discover new gene expression patterns important for your research.

Together with Proteona鈥檚 data analysis support, the ESCAPE CAR T assay provides rich information that can be used at all stages of the CAR T workflow, from initial cell collection to post infusion patient monitoring.

The Proteona CAR T assay is based on the Enhanced Single Cell Analysis with Protein Expression (ESCAPE) RNA sequencing technology, which uses DNA-barcoded antibodies to capture proteomic and gene expression data simultaneously at the single cell level.

CAR T cells are a promising therapy against aggressive blood cancers and solid tumors. They are manufactured from T cells, immune cells that are able to recognize specific markers on pathogens or abnormal cells and destroy them.

To manufacture CAR T, human T cells are harvested and then modified to target specific cancer antigens, so that they are able to find and kill cancer cells once infused back to the patient. CAR T manufacturing is a complex process, and there is a large range of variations in patient response in terms of toxicity and efficacy.

It is still not clear what the mechanisms are that determine the safety and functionality of CAR T cell treatment. The new CAR T ESCAPE assay now provides a comprehensive tool to shed light on the complex CAR T mechanisms, opening a new path for the development of safer cell therapies.

Click here for the complete issue.

NEWS CRUNCH  
news Technology giant, Tencent Holdings Limited, promotes medical science and healthcare
news ECV2019 China Healthcare and Pharma Digital Innovation Summit Held Successfully in Shanghai — The "Highway" Era of Healthcare Digital Transformation
news Natural Extracts Innovated, Transformed and Diversely Laid Out to Embrace the Blue Ocean Market of Big Health
news The Proteona Oncology Challenge using ESCAPETM Single Cell Proteogenomic Analysis
PR NEWSWIRE  
Asia Pacific Biotech News
SPOTLIGHT  
LIFE OF A SCIENTIST  

APBN Editorial Calendar 2019
January:
Taiwan Medical tourism
February:
Marijuana as medicine — Legal marijuana will open up scientific research
March:
Driven by curiosity
April:
Career developments for researchers
May:
What's cracking — Antibodies in ostrich eggs
June:
Clinical trials — What's in a name?
July:
Traditional Chinese medicine in modern healthcare — Integrating both worlds
August:
Digitalization vs Digitization — Exploring Emerging Trends in Healthcare
September:
Healthy Ageing — How Science is chipping in
October:
Disruptive Urban Farming — Microbes, Plasmids, and Recycling
November:
Evaluating cost effectiveness of genomic profiling
Editorial calendar is subjected to changes.
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