HOME ABOUT CONTACT AVAILABLE ISSUES SUBSCRIBE MEDIA & ADS
LATEST UPDATES » Vol 23, No 11, November 2019 – Evaluating cost effectiveness of genomic profiling       » Ion treatment offers new hope for cancer patients       » Empowering sustainability through innovation       » Meeting clinical needs in Asia with HealthTech       » The key in diagnosis and treatment       » Singapore's first private co-working laboratory and office space       » Singapore-based MedTech company announced as winner of 2019 Asia Pacific Showcase Competition at The MedTech Forum      
Vol 23, No. 11, November 2019For e-subscribers (PDF)
EYE ON CHINA
Researchers Try "One-Two Punch" Method to Treat Liver Cancer
An international team of researchers have found a "one-two punch" method to treat liver cancer by inducing weakness in liver cancer cells and exploiting the vulnerability to reduce tumour growth.

Researchers from Shanghai Jiao Tong University's School of Medicine and the Netherlands Cancer Institute found they can selectively induce senescence in liver cancer cells with mutations in a gene named TP53.

Senescence means the loss of a cell's power of division and growth, similar to putting the cell into a sleep mode.

The researchers said that the cells in the sleep mode have an "acquired vulnerability" and a follow-up screening will select a suitable chemical agent to target the vulnerability and kill cancer cells.

They said the two-step treatment is like the classic "one-two punch" from boxing. A combination of two blows is delivered in rapid succession: a left jab to expose the cancer cell's weak points quickly followed by a right cross to knock them out.

Meanwhile, the treatment has minimal side effects on other cells in normal proliferation, they added.

According to the research published in the journal Nature early this month, the treatment resulted in a marked reduction of tumor growth in mouse models of liver cancer.

The researchers said their study indicates that exploiting an induced vulnerability could be an effective treatment for liver cancer.

Liver cancer is a common malignant tumor with poor prognosis. Surgery and liver transplants so far are the most effective treatments. However, due to the difficulty of early diagnosis and rapid progression of the disease, most patients are unable to undergo surgery when they are diagnosed.

(Source: Xinhua)

Click here for the complete issue.

NEWS CRUNCH  
news ECV2019 China Healthcare and Pharma Digital Innovation Summit Held Successfully in Shanghai — The "Highway" Era of Healthcare Digital Transformation
news Natural Extracts Innovated, Transformed and Diversely Laid Out to Embrace the Blue Ocean Market of Big Health
news The Proteona Oncology Challenge using ESCAPETM Single Cell Proteogenomic Analysis
news New computational fluid dynamics solution for modeling aerosol mixtures in biomedical and environmental research
PR NEWSWIRE  
Asia Pacific Biotech News
SPOTLIGHT  
LIFE OF A SCIENTIST  

APBN Editorial Calendar 2019
January:
Taiwan Medical tourism
February:
Marijuana as medicine — Legal marijuana will open up scientific research
March:
Driven by curiosity
April:
Career developments for researchers
May:
What's cracking — Antibodies in ostrich eggs
June:
Clinical trials — What's in a name?
July:
Traditional Chinese medicine in modern healthcare — Integrating both worlds
August:
Digitalization vs Digitization — Exploring Emerging Trends in Healthcare
September:
Healthy Ageing — How Science is chipping in
October:
Disruptive Urban Farming — Microbes, Plasmids, and Recycling
November:
Evaluating cost effectiveness of genomic profiling
Editorial calendar is subjected to changes.
MAGAZINE TAGS
About Us
Events
Available issues
Editorial Board
Letters to Editor
Instructions to Authors
Advertise with Us
CONTACT
World Scientific Publishing Co. Pte. Ltd.
5 Toh Tuck Link, Singapore 596224
Tel: 65-6466-5775
Fax: 65-6467-7667
» For Editorial Enquiries:
   biotech_edit@wspc.com or Ms Deborah Seah
» For Subscriptions, Advertisements &
   Media Partnerships Enquiries:
   biotech_ad@wspc.com
Copyright© 2019 World Scientific Publishing Co Pte Ltd  •  Privacy Policy