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LATEST UPDATES » Vol 23, No 03, March 2019 – Driven by curiosity — Exclusive interview with Nobel laureate Ada Yonath: Her journey in science wasn't always crystal clear       » Your eyes don't deceive you, your brain does       » Organ donations to be computerised in China       » Over One tenth of Chinese people have mental health problems       » AI system can diagnose childhood diseases like doctors       » Bitter rapeseed potential protein source for human nutrition      
NEWS CRUNCH
Runners' High, Happy Feet — If you're Happy, and you know it 'Clap' your Feet

6th October 2015- A group of researchers in Germany recently published findings evidencing that runner's high is not just caused by exercise-induced endorphin release. A runner's high is a subjective sense of well-being some people experience after exercising for long periods of time. For decades, it was hypothesized that runner's high is caused by exercise-induced endorphin release. Long-distance runners have always described a runner's high as a sudden pleasant feeling of euphoria, anxiolysis, sedation, and analgesia. However, running increases blood levels of both endorphin (an opioid) and anadamide (an endocannabinoid).

The paper published by Fuss and colleagues shows that endocannabinoids may play a role. Using a combination of pharmacological, molecular genetics, and behavioral studies in mice, they discovered that wheel running increases endocannabinoids and reduces both anxiety and sensation of pain in mice. With the conclusion that for the first time, cannabinoid receptors are crucial for main aspects of a runner's high and not just exercise-induced endorphin release as perceived before. Sedation, in contrast, was not influenced by cannabinoid receptors and euphoria cannot be studied in mouse models.

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Johannes Fuss et. al. A runner's high depends on cannabinoid receptors in mice. https://www.pnas.org/cgi/doi/10.1073/pnas.1514996112

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APBN Editorial Calendar 2019
January:
Taiwan Medical tourism
February:
Marijuana as medicine — Legal marijuana will open up scientific research
March:
Driven by curiosity
Editorial calendar is subjected to changes.
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