LATEST UPDATES » Vol 26, Nos. 05 & 06, May & June 2022 – Living Better for Longer: Cutting-Edge Research in Geriatric Medicine       » How Oxidation Can Lead to Mitochondrial Dysfunction and Age-Dependent Cognitive Disorders       » New Semiconductor Microchip Detects Prostate Cancer Markers With Ultra-High Sensitivity       » New Method for Synthesising Sulphur-Based Medicines Can Boost Drug Discovery Efficiency and Speed       » Selecting the Best Target for Deep Brain Stimulation in Parkinson’s Disease       » A Single Metabolite Can Promote Tissue Regeneration and Delay Ageing       » A New Light-Sensitive Way to Control Parathyroid Hormone Secretion for the Prevention of Bone Loss      
Vol 25, No. 08, August 2021   |   Issue PDF view/purchase
But What Is Cancer, If Not Cells Persevering?

Cancer is characterised by the uncontrolled division of cells. While our cells have a built-in proofreading mechanism to ensure that the DNA bases encoded is the right one, the more times a cell divides, the higher the probability that an error may occur. Such errors could contribute to uncontrolled cell division, where cells continue to persist within our bodies, ignoring signals that normally tell cells to stop dividing or to die.

We have known about cancer for a long time, with the earliest description of the disease dating back to 3000 B.C. in Egypt. Fast forward to the present day, why have we not yet found a cure for cancer?

Our bodies are incredibly dynamic. Apart from ignoring growth signals, cancer cells can hide from the immune system, manipulate the immune system to help them grow, accumulate more mutations that might render the current treatment less effective, and many more.

This might seem like an impossible battle, but great strides have been made towards understanding the factors that contribute to cancer development, putting us in a better position than before to prevent or manage the disease.

In this issue, we have a deeper look at some of the progress made in cancer research. First off, Yie Hou Lee and Michael Birnbaum from the Singapore-MIT Alliance for Research and Technology Critical Analytics for Manufacturing Personalized-Medicine (SMART-CAMP) share about the future of CAR T cell manufacturing (p.26). Next, a team of researchers from the National Neuroscience Institute, National University of Singapore, and the Duke-NUS Medical School considers the difficulty of treating glioblastoma brain tumours and how they plan to address its critical issues (p.32). Finally, Dr. Chi-Jui Liu and Hsiao Yun Lu talk about hereditary cancers and how we may improve our odds in this game of roulette (p.37).

Shifting away from cancers, we have in our Columns, an analysis by Dr. Ping-Chung Leung on the integrative use of Traditional Chinese Medicine in managing treatment outcomes of COVID-19 patients (p.16) and a reflection by Dr. Chris Nave on the lessons we can take away from the development of COVID-19 vaccines (p.24).

In our Spotlights section, we share highlights from the Vaccines World Summit 2021 (p.42) and an interview with Mr. Abel Ang, Group Chief Executive of Advanced MedTech on how their new venture AbAsia Biolabs can help meet Singapore’s need for increased COVID-19 test kits as we enter a new normal (p.46).

Lastly, in our News section, we highlight some significant breakthroughs in cancer research with the use of deep neural networks in predicting cancer (p.61), finding clues into what drives cancer (p.8,9), and looking at how we can make tumours eliminate themselves (p.71).

Carmen Chan
You can reach me at [email protected]


You can always access all APBN's issues on our website: www.asiabiotech.com.
Check us out at Facebook @Asia Pacific Biotech News, Instagram @asiabiotech, or follow us on Twitter @asia_biotech.


MGI Makes Possible New Advances in Agrigenomics Research and Molecular Breeding
news Medtec China 2022 Gathers Medtech Leading Enterprises, Optimising Medical Equipment Supply Chain by Creating Online-Offline Promotion Platforms
news Medtec China 2022 Is Now Open for Visitor Registration, Helping Medical Device Manufacturers in Medtech Sourcing and Supply Chain Stabilisation
news Inaugural Asia Summit on Global Health highlights Hong Kong's advantages
news Asia Summit on Global Health (ASGH) 2021 — Shaping a Resilient and Sustainable Future

About Us
Available issues
Editorial Board
Letters to Editor
Contribute to APBN
Advertise with Us
World Scientific Publishing Co. Pte. Ltd.
5 Toh Tuck Link, Singapore 596224
Tel: 65-6466-5775
Fax: 65-6467-7667
» For Editorial Enquiries:
   [email protected] or Ms Carmen Chan
» For Subscriptions, Advertisements &
   Media Partnerships Enquiries:
   [email protected]
Copyright© 2022 World Scientific Publishing Co Pte Ltd  •  Privacy Policy