APBN has received a complimentary iGene prenatal test kit, and we like to send it out to one of our lucky readers. It is an open book test. All you have to do is to read the following text, and answer the following question, how many liter(s) of blood sample is required to run one iGene test?
Send your answers to [email protected] by 20th December 2015.
i) How is iGene® different from other prenatal test kits?
iGene® is a non-invasive prenatal test (NIPT) that analyses cell-free DNA to detect Down Syndrome (Trisomy 21), Edwards Syndrome (Trisomy 18) and Patau Syndrome (Trisomy 13) with more than 99% accuracy. [1,2]
The non-invasive prenatal test is based on the world's largest published study of over 146,000 pregnancies among women who are considered average to high-risk. It is also the non invasive prenatal test with the lowest non-reportable rate of 0.1% compared to other tests. [3,4,5] From the published findings, iGene test has a low false positive rate of 0.05% for Trisomy 21, Trisomy 18 and Trisomy 13. It can be tested on egg donor, IVF and twin pregnancies. 
The test results can be obtained between 7 - 10 working days upon receipt in our laboratory.
ii) What should mothers know about prenatal tests for twin pregnancies? Is iGene® test sufficient to identify abnormalities in twin pregnancies?
iGene® can be tested on twin pregnancies. One sample of 10ml of maternal blood sample is sufficient to run the test. iGene® has an extremely high sensitivity and specificity for twin pregnancies. 
Source: Dr. Francisco M. Gil-Salas from iGene
iGene Non Invasive Prenatal Test Collection Kit is available at private hospitals and clinics in Singapore.
N.B: Prior to any medication and diagnostic test, patients must seek medical advice from a certified medical doctor or medical specialist. APBN is not liable for patients' safety for any product published in the magazine.
- Dan et al., 2012 Prenatal Diagnosis 32;1-8.
- Jiang F, et al. 2012 BMC Medical Genomics 5:57.
- Zhang H, et al. 2015 Ultrasound Obstet. & Gynecol. 45: 530-538.
- Norton et al. 2015 N Engl J Med 372, 1589-1597.
- Dar, P et al. 2014. Am J Obstet Gynecol.